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As they grow older, they tend to become taller than average.They may have less muscle control and coordination than other boys of their age.

Although they can face problems during adolescence, often emotional and behavioral, and difficulties at school, most of them can achieve full independence from their families in adulthood. The results of a study carried out on 87 Australian adults with the syndrome shows that those who have had a diagnosis and appropriate treatment from a very young age had a significant benefit with respect to those who had been diagnosed in adulthood.Fertilizing a double X egg with a normal sperm also produces an XXY offspring (Klinefelter).Another mechanism for retaining the extra chromosome is through a nondisjunction event during meiosis II in the egg.Nondisjunction will occur when sister chromatids on the sex chromosome, in this case an X and an X, fail to separate.

(meiosis) An XX egg is produced which, when fertilized with a Y sperm, yields XXY offspring.About 10% of XXY males have gynecomastia noticeable enough that they may choose to have cosmetic surgery.